Altasciences has significant experience in cannabis, nicotine and tobacco product studies, both in the U.S. and Canada. We are invited members of the CORESTA (Cooperation Center for Scientific Research Relative to Tobacco) subcommittee on Smoking Behavior and Biomarkers, where we actively contribute to white papers concerning the latest requirements for clinical pharmacology studies needed for regulatory submission.
Since 2016, we have conducted more than 10 studies on electronic nicotine delivery systems (ENDS) or heat-not-burn products, with endpoints ranging from abuse potential, nicotine pharmacokinetics, and biomarkers of exposure and harm, to topography. Our clinics have specially-designed smoking rooms with dedicated air handling systems, as well as robust databases of participants who smoke and/or vape.
Our bioanalytical lab has been analyzing nicotine in blood and total urinary nicotine equivalents for years, and has developed a robust SOP for nicotine decontamination that ensures staff or participants do not contaminate the tubes. We recently validated the biomarkers of exposure, such as for tobacco specific nitrosamines (TSNAs).
- 50,000+ smokers in our database
- 10+ studies on vaping products since 2016
Notre vaste expertise et nos capacités approfondies dans toute une gamme de domaines thérapeutiques visent notamment les études précliniques et cliniques pour les petites et grandes molécules. Nous pouvons gérer l’ensemble de votre programme et vous fournir des services de soutien à la recherche, et nous mettons à votre disposition notre expertise bioanalytique de grande renommée.